Best Telemedicine for Compounded Semaglutide & Tirzepatide 2026

Updated 2026-05-08·By GLP1CompareHub Editorial Team

Compounded GLP-1 medications (compounded semaglutide and compounded tirzepatide) are produced by state-licensed 503A patient-specific compounding pharmacies under specific FDA exemptions. They are NOT FDA-approved drugs. Compounded options are typically 60–90% cheaper than branded equivalents. Heightened FDA scrutiny since the April 30, 2026 proposed bulks-list exclusion — providers with verified 503A sourcing and accredited pharmacy partners now stand out.

Quick Nav:#1 OrderlyMeds #2 GobyMeds #3 SkinnyRx #4 Eden Health #5 TMates

Best Overall

OrderlyMeds

From

$149–$299 compounded, $1,498–$1,839 branded

4.5

Personalized GLP-1 + $3,700 value bundle

Why #1? OrderlyMeds is one of only two providers in our stack with a public affiliate program. The lifestyle bundle (BetterHelp + Trifecta + dietitian + fitness app) is the strongest value-add in the stack. Apply to affiliate program FIRST.

Pros

PUBLIC affiliate program (/affiliate-program/get-started/)
Includes BetterHelp mental health therapy (high-perceived-value bundle)
Trifecta meal service 50% off

Cons

Branded GLP-1 ($1,498–$1,839) is high anchor pricing
3-month starter pricing requires upfront commitment

Full Review Visit OrderlyMeds

Best Value

GobyMeds

From

From $99/mo (compounded sema)

4.6

Compounded GLP-1 with B12/NAD+ stack add-ons

Why #2? GobyMeds is the price leader in our stack ($99/mo entry) AND has the most accessible affiliate program (two-track public signup). Strong "Best Value" or "Best Entry-Level" candidate. Apply to affiliate program FIRST.

Pros

LOWEST entry price in our verified stack ($99/mo)
Unique GLP-1 + B12/NAD+/glycine combo additives
No subscription/membership fees

Cons

Lower entry pricing may correlate with shorter consult time
Branded GLP-1 pricing not displayed on site

Full Review Visit GobyMeds

Best Brand-Name Value

SkinnyRx

From

$199–$399

4.9

503A compounded GLP-1 specialist

Why #3? SkinnyRx is the strongest verified-CPA affiliate program in our stack as of May 2026. The 503A compliance angle is a real differentiator for compliance-conscious patients. Catalog details require manual screenshot to fully verify.

Pros

Highest-rated affiliate program in verified May 2026 stack
Bundled monthly pricing — consult, prescription, shipping included
503A pharmacy compliance — established regulatory track record

Cons

Compounded only — no branded GLP-1 (Wegovy/Zepbound) options
Lab work not included in base price
Full product catalog not externally visible (SPA architecture)

Full Review Visit SkinnyRx

Best Clinical Outcomes

Eden Health

From

$149 intro / $229–$249 ongoing

4.7

Branded + compounded with intro pricing

Why #4? Eden Health is the broadest-catalog provider in our verified stack and has the strongest verified member count (127K+). The NAD+ ecosystem alone is a category they own. Strong "Best Value" or "Best for Wellness Stack" candidate.

Pros

"Same Price at Every Dose" — no titration upcharge
127,000+ members (largest verified userbase)
NAD+ in 5 different formats — owns the category

Cons

3-month plan pricing requires upfront commitment for lowest rate
Monthly-without-commitment pricing higher ($229-249)

Full Review Visit Eden Health

Best for Beginners

TMates

From

Semaglutide $158-$249/mo, Tirzepatide $167-$297/mo (1-12 mo plans)

4.7

Highest-converting GLP-1 program in our stack — semaglutide + multi-vertical

Why #5? TMates GLP1 is the standout performer in our Katalys stack — $16.09 EPC and 6.43% CR are data that command attention. A $250 CPA combined with that conversion rate makes it the highest revenue-per-click program we run. Should be featured prominently once pricing is verified and detail page is built.

Pros

#1 highest EPC in our entire Katalys account ($16.09 — Katalys-verified May 2026)
6.43% conversion rate — exceptional for GLP-1 telehealth vertical
$250 CPA per sale

Cons