TMates Review 2026
Best OverallThe #1 highest realized EPC ($16.09) and conversion rate (6.43%) in our active May 2026 Katalys stack. Same price across every dose tier — sema $158-$249/mo, tirz $167-$297/mo — with deep volume discounts on longer plans. Injectable AND oral compounded GLP-1 under one intake.
EPC and CR are realized affiliate metrics from the Katalys partner dashboard, not estimates. TMates ranks #1 in our entire active stack on both. 2,400+ patients. Updated May 13, 2026.
TL;DR — Who TMates Is For
- You can commit to a 6 or 12-month plan and want the deepest discount in our verified stack (37% off sema, 44% off tirz)
- You want flat-rate pricing across every dose tier (no titration upcharge from 2.5mg to 15mg)
- You want both injectable and oral GLP-1 options under one provider intake
- You’re building a multi-vertical stack (GLP-1 + NAD+, TRT, or ED treatment under one provider)
- You want branded Wegovy or Zepbound (TMates is compounded-only)
- You want the lowest single-month price (System Labs at $179/mo or Strut Health at $99/mo oral wins)
- You can’t commit to 6+ months upfront (TMates’ best pricing requires longer commitment)
- You want the broadest adjacent peptide menu (Eden Health’s 5-format NAD+ wins)
Same Price Across Every Dose Tier
Most compounded GLP-1 telehealth providers raise prices as your dose escalates from the starter to therapeutic maximum. TMates’ same-price model locks your monthly cost regardless of where you sit in the titration schedule — meaningful because most patients land at 7.5mg-15mg tirzepatide or 1.7mg-2.4mg semaglutide for full therapeutic effect.
| Plan Length | Semaglutide | Tirzepatide | Savings vs Monthly |
|---|---|---|---|
| 1 month (any dose) | $249 | $297 | — |
| 3 months | $217/mo | $267/mo | 13% / 10% |
| 6 months | $175/mo | $217/mo | 30% / 27% |
| 12 months | $158/mo | $167/mo | 37% / 44% |
Pricing live-crawled from tmates.com/products/semaglutide and /tirzepatide on May 6, 2026. Same price applies across all dose tiers — sema 0.25mg to 2.4mg, tirz 2.5mg to 15mg. The 12-month tirzepatide rate ($167/mo) is among the most competitive long-term pricing in our verified May 2026 stack — meaningfully below the typical $250-$400 range at therapeutic dose tiers from other providers.
Multi-Vertical Menu — One Provider, Many Programs
TMates patients can layer GLP-1 weight loss with adjacent programs from the same provider — meaning one intake, one prescriber relationship, one shipping account for multiple care lines. The full menu spans GLP-1 (injectable + oral), longevity peptides (NAD+), hormone therapy (TRT), sexual health (ED), skin care, and hair loss (men’s and women’s).
Compounded GLP-1 (injectable)
Semaglutide + Tirzepatide. Same price all doses. 1/3/6/12-month plans.
Compounded GLP-1 (oral)
Oral semaglutide and oral tirzepatide for needle-averse patients. Lower bioavailability but no-injection delivery.
NAD+ Therapy
Longevity stack adjacent to GLP-1. Cross-sell potential for patients building a comprehensive weight + energy + longevity protocol.
TRT (Testosterone Replacement)
Hormone optimization for eligible patients. Common GLP-1 + TRT combo for men addressing weight + low T together.
ED / Sexual Health
Sildenafil and tadalafil prescriptions through the same provider — common comorbidity with metabolic conditions.
Hair Loss (M + F)
Men's and women's hair regrowth — finasteride, minoxidil, and topical formulations.
See our NAD+ IV therapy guide and oral tirzepatide deep-dive for the full evidence read on each format.
TMates vs the Field — Where It Wins and Loses
vs Embody ($149 first / $299 flat)
→ TMates on long-term price, Embody on month-1 entryEmbody's Spring Forward promo lands at $149 first month with $299 flat refills regardless of dose. TMates is $249 first month at sema (any dose) but drops to $158/mo on the 12-month plan — meaningfully cheaper than Embody's $299 for committed patients. Embody wins on month-1 entry cost; TMates wins on sustained 12-month cost. Embody's realized EPC ($4.60) and CR (1.31%) are second in our stack; TMates is #1 by a wide margin on both.
vs Eden Health ($149 first / $229-$249 flat)
→ TMates on long-term value, Eden on adjacent peptide breadthEden's $229-$249 ongoing range is cheaper than TMates' monthly plan but more expensive than TMates' 12-month plan ($158-$167/mo). Eden also offers branded Wegovy and Zepbound; TMates is compounded only. Eden has the broader adjacent-peptide menu (NAD+ in 5 formats); TMates is more streamlined (NAD+ as a single program). Pick Eden for established brand + branded fallback; pick TMates for the deepest discount on a committed plan.
vs System Labs ($179/mo)
→ System Labs on cheapest sustained price, TMates on conversion data + multi-verticalSystem Labs is $179/mo flat — the lowest sustained compounded GLP-1 price in our verified stack. TMates' 12-month plan ($158-$167/mo) actually beats System Labs at therapeutic doses if you can commit, but on a month-by-month basis System Labs wins on price. System Labs is GLP-1-focused; TMates is multi-vertical (GLP-1 + NAD+ + TRT + ED + Hair). System Labs also doesn't have realized Katalys data yet.
vs Strut Health ($99/mo oral sema, $199/mo oral tirz)
→ Strut Health on cheapest oral entry, TMates on injectable + multi-verticalStrut is $99/mo oral semaglutide — the lowest verified GLP-1 entry price in our stack — and offers no-video async physician review. But Strut is ORAL ONLY. TMates is the only provider in the stack with both injectable AND oral options across both sema and tirz, plus the deepest multi-vertical menu. Pick Strut for cheapest oral entry + no-video; pick TMates for full delivery flexibility + multi-vertical.
vs Gala Health ($179-199 3-mo bundled)
→ Gala on bundled 3-month, TMates on 6/12-mo and dose-flat pricingGala's 3-month plan is $179-$199/mo all-inclusive. TMates' 3-month plan is $217-$267/mo — more expensive at 3 months. But at 6 months ($175-$217/mo) and 12 months ($158-$167/mo), TMates pulls ahead. Gala is GLP-1 specialized; TMates is multi-vertical. Both flat-rate the dose tier. Pick Gala for the cheapest 3-month commitment; pick TMates if you'll commit to 6+ months.
Compliance + Pharmacy Sourcing (May 2026)
TMates sources compounded medications through a licensed compounding pharmacy partner. Post-April 1 2026 FDA enforcement shift, providers operating in this space must demonstrate patient-specific 503A compounding compliance — TMates continues serving customers under that narrower exception as of May 2026. The 2,400+ patient base gives a multi-cohort operational track record, though shorter than Eden Health’s.
Compounded-only providers like TMates carry tighter regulatory exposure than dual-supply providers (Eden Health offers both branded and compounded). If the April 30 503B exclusion proposal finalizes after the June 29 comment period, compounded-only providers face higher continuity-of-supply risk than providers with branded fallback. Worth weighing for patients planning 12-month commitments.
Pros and Cons (Honest Read)
- #1 highest EPC in our entire Katalys account ($16.09 — Katalys-verified May 2026)
- 6.43% conversion rate — exceptional for GLP-1 telehealth vertical
- $250 CPA per sale
- Multi-vertical: GLP-1, NAD+, TRT, ED, Hair — cross-sell funnel depth
- Same price across all dosages (sema 0.25-2.4mg, tirz 2.5-15mg) — predictable cost as dose escalates
- Compounded GLP-1 only (no branded Wegovy/Zepbound)
- 12-month plan required for the lowest per-month price tier
Start TMates from $158/mo on the 12-Month Plan
Same price across every dose tier. Injectable and oral GLP-1 options. Multi-vertical menu spanning NAD+, TRT, ED, hair, and skin under one intake. Cancel anytime — though the deepest discounts (37%/44%) require the 12-month commitment.
Compare TMates to Other Verified Providers
Five other Katalys-active programs. Pricing verified May 2026.
Other Verified Compounded GLP-1 Programs
Pricing accurate as of May 2026. Click a provider to see current pricing and start a consultation. We may earn a commission — at no extra cost to you. See our affiliate disclosure.
| Provider | Monthly Price | Rating | Action |
|---|---|---|---|
SkinnyRxBest Overall 503A compounded GLP-1 specialistCompounded Tirzepatide + Semaglutide (503A pharmacy) | $199–$399 | ★★★★★4.9 | View Best Offer |
TrimRx Online weight loss program with GLP-1 medicationGLP-1 weight loss program (catalog VERIFY) | From $179/mo | ★★★★☆4.5 | View Best Offer |
MEDViEditor’s Pick Reliable mid-tier compounded GLP-1Compounded Tirzepatide + Semaglutide | $179–$299 | ★★★★☆4.6 | View Best Offer |
DirectMedsBest for Sublingual Sublingual + injectable compounded GLP-1Compounded Sema + Tirz (injectable + sublingual), Sermorelin, NAD+, Epithalon | $179–$399 | ★★★★☆4.5 | View Best Offer |
Ivim HealthBest for Microdosing 360 wellness — branded + compounded + microdosing GLP-1Compounded Sema/Tirz/Liraglutide, microdosing GLP-1, Wegovy/Zepbound/Mounjaro/Ozempic/Saxenda, Wegovy Pill | From $75/mo + $74.99 program fee | ★★★★☆4.7 | View Best Offer |
Pricing and availability current as of May 2026. We earn a commission if you sign up through our links — at no additional cost to you. See our methodology for how we evaluate providers.
Related Guides
Continue your research with these related independent reviews.
Same price at every dose, lowest sustained cost.
12-month plans: $158/mo semaglutide, $167/mo tirzepatide. Cancel anytime.